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[Intra-abdominal hypertension and abdominal compartment syndrome in patients with severe sepsis and septic shock].
To investigate the incidence, clinical features and outcome of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) in patients with severe sepsis and septic shock. This prospective study included a total of 117 patients with severe sepsis or septic shock who were admitted to intensive care unit (ICU) of Xuanwu Hospital during July and October in 2010. The clinical and laboratory data were collected within 24 hours after admission. The definition of IAH and ACS was as follows: IAH was defined as a sustained or repeated intra-abdominal pressure (IAP) of 12 mmHg or higher associated with new organ dysfunction; and ACS was defined as the presence of IAH plus abdominal organ dysfunction requiring intervention. The incidence of IAH/ACS was 41.0% (47/117). The incidence of ACS was 23.1% (26/117), while the incidence of IAH was 19.7% (22/117). Patients with IAH/ACS had a higher rate of gastrointestinal perforation than the patients without IAH/ACS [29.8% (8/26) vs. 10.4% (14/133), P 0b46394aab